Home » Archive » Volume 2 (2011) » Issue No.1 » Bioactive lipids in atherosclerosis

Bioactive lipids in atherosclerosis

U.N. Das, MD, FAMS1 

  1. UND Life Sciences, 13800 Fairhill Road, #321, Shaker Heights, OH 44120, USA, School of Biotechnology, Jawaharlal Nehru Technological University, Kakinada-533 003, India and Bio-Science Research Centre, Gayatri Vidya Parishad College of Engineering, Visakhapatnam, India

Pages: 11-18


Atherosclerosis is a low-grade systemic inflammatory condition and a dynamic process. Recent evidences suggest that anti-inflammatory products of polyunsaturated fatty acids such as lipoxins, resolvins, maresins and nitrolipids play a significant role in atherosclerosis by modulating the functions of platelets, leukocytes and macrophages and by protecting endothelial cells from the actions of reactive oxygen species. Hence, methods designed to enhance the formation of these bioactive anti-inflammatory lipids could be employed in the prevention and management of atherosclerosis.


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