[authors]<\/p>\n
Michalis Georgoulis<\/a>,\u00a0Christina Katsagoni<\/a>,\u00a0Nafsika Tileli<\/a>,\u00a0Meropi D. Kontogianni<\/a><\/p>\n [\/authors]<\/p>\n [summary]<\/p>\n Non Alcoholic Fatty Liver Disease (NAFLD) is a clinicopathologic entity with wide histological spectrum which\u00a0includes both simple steatosis and steatohepatitis (NASH). NAFLD is considered as the hepatic manifestation of the metabolic\u00a0syndrome and is strongly associated with cardiovascular disease, while the most prevailing mechanism underlying the\u00a0pathogenesis of NAFLD is insulin resistance. Nutrition is considered as an important component of both the pathogenesis\u00a0and the treatment of NAFLD. The purpose of this review is to present all the existing data correlating dietary habits with the\u00a0incidence of NAFLD, as well as clinical studies that include treatment by dietary intervention. Studies that have explored the\u00a0role of diet in the pathogenesis of NAFLD are mainly case-control studies with retrospective data collection and do not reveal\u00a0any prominent benefit or deficit of any of the macronutrients or their subclasses in the incidence of the disease. Moreover\u00a0studies exploring the association between antioxidants intake and the risk of NAFLD remain contradictory. Regarding NAFLD\u00a0management, weight loss for the overweight subjects is the cornerstone therapy weather it is achieved with diet alone or\u00a0with a combination of diet and exercise. However, the impact of diet\u2019s composition on the disease management remains\u00a0uncertain. Based on the available evidence, there is a need for well designed prospective studies to explore the role of diet\u00a0as a risk factor for NAFLD, as well as for randomized controlled clinical trials to define the best nutritional management for\u00a0the disease.<\/p>\n [\/summary]<\/p>","protected":false},"excerpt":{"rendered":" Non Alcoholic Fatty Liver Disease (NAFLD) is a clinicopathologic entity with wide histological spectrum which includes both simple steatosis and steatohepatitis (NASH).<\/p>\n","protected":false},"author":402,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[57],"tags":[],"_links":{"self":[{"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/posts\/157"}],"collection":[{"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/users\/402"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/comments?post=157"}],"version-history":[{"count":0,"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/posts\/157\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/media?parent=157"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/categories?post=157"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjnutrdiet.gr\/en\/wp-json\/wp\/v2\/tags?post=157"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}